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Vetoryl (Trilostane)

Vetoryl Capsules Main About VETORYL® Capsules (trilostane)

VETORYL® Capsules (trilostane) is a prescription medication prescribed to aid in your dog’s treatment of hyperadrenocorticism—also known as Cushing’s Disease. This medication treats both pituitary-dependent and adrenal-dependent cases, and controls the excess production of cortisol caused by the disease.

VETORYL® Capsules (trilostane) are the only FDA approved treatment available for both pituitary-dependent hyperadrenocorticism (PDH) and adrenal-dependent hyperadrenocorticism (ADH) in the United States. Although the daily administration of VETORYL Capsules does not offer a medical cure for Cushing’s syndrome, it may allow the disease to be managed successfully, enhancing the dog’s vitality and quality of life.

A Few Facts about VETORYL Capsules:

  • VETORYL Capsules contain trilostane, which selectively, and reversibly, inhibits the enzyme 3βs-hydroxysteroid dehydrogenase, which is involved in the synthesis of several steroids including cortisol and aldosterone
  • At recommended dose rates, VETORYL Capsules tend to have a more selective effect on glucocorticoid production, however the potential inhibition of aldosterone must always be borne in mind by the attending clinician
  • VETORYL Capsules reduce circulating cortisol levels, leading to improvement in many of the clinical signs of HAC
  • VETORYL Capsules provide flexible and accurate dosing with five strengths, 5 mg, 10 mg, 30 mg, 60 mg and 120 mg capsules, allowing you to restore the dog’s vitality by reducing the clinical signs associated with HAC
  • Available in blister packs of 30 capsules for ease of dispensing.


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