Antihistamines are given to relief and stop histamine secretion in the body. Histamines are released from mast cell degranulation and it can lead to excessive inflammation.
Some of the most common antihistamines used in dogs are Benadryl (diphenhydramine), Zyrtec (cetirizine), and Claritin (loratadine). They relieve allergy symptoms by counteracting allergic reactions due to histamine release in the blood stream.
Antihistamines are usually safe but make some dogs drowsy and others hyperactive.Â
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