When antibodies bind to persistent antigens, they can create immune complexes. These antigen-antibody complexes can get lodged in small blood vessels and stimulate inappropriate inflammation of the surrounding tissue. Immune complex disorders are among the most common immune-mediated diseases. The location in the body where the immune complexes are deposited determines the signs and the course of the disease.
Immunosuppressant medications help in decreasing the body response and inflammation.
source:https://www.merckvetmanual.com
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